Romifenone

Romifenone

SCHEMBL2109098

O=C(CCN1CCOCC1)c1ccccc1O

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.66
MAPT P10636 5/20 0.66
KMT2A Q03164 4/20 0.66
LMNA P02545 2/20 0.54
MPI P34949 1/20 0.54
CYP2C19 P33261 1/20 0.54
HSP90AA1 P07900 1/20 0.53
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
ABCB1 P08183 1/20 0.50
EGFR P00533 1/20 0.50
MGLL Q99685 1/20 0.50
TP53 P04637 1/20 0.50
ALDH3A1 P30838 1/20 0.50
HTT P42858 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12123783 0.84 ALDH1A1 (0.64) ALDH1A1MAPTKMT2ALMNAMPI
SCHEMBL12123820 0.84 KMT2A (0.64) ALDH1A1MAPTKMT2ALMNAMPI
SCHEMBL7465394 0.84 ALDH1A1 (0.64) ALDH1A1MAPTKMT2ALMNAMPI
SCHEMBL12123807 0.84 ALDH1A1 (0.64) ALDH1A1MAPTKMT2ALMNAMPI
Hydrochloric Acid SCHEMBL7930415 0.82 ALDH1A1 (0.65) ALDH1A1MAPTKMT2ALMNAMPI
SCHEMBL12123784 0.81 ALDH1A1 (0.70) ALDH1A1MAPTKMT2A
SCHEMBL17177575 0.81 ALDH1A1 (0.61) ALDH1A1MAPTKMT2ALMNAMPI
SCHEMBL12123822 0.80 KMT2A (0.59) ALDH1A1MAPTKMT2ALMNAMPI
SCHEMBL321369 0.80 ALDH1A1 (1.00) ALDH1A1MAPTKMT2ALMNAMPI
Hydrochloric Acid SCHEMBL7932175 0.79 ALDH1A1 (0.70) ALDH1A1MAPTKMT2AABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20250017879-A1 COMPOSITION WITH VIRUCIDAL ACTIVITY, USE AND APPLICATION THEREOF Bio Logic Crop Science S.L. (ES) 2025-01-16 US disclosed
EP-4427745-A1 COMPOSITION WITH VIRUCIDAL ACTIVITY, USE AND APPLICATION METHOD THEREOF Bio Logic Crop Science, S.L. (ES) 2024-09-11 EP disclosed
US-11766364-B2 Wound closure systems for reducing surgical site infections comprising incision drapes filled with releasable antimicrobial agents ETHICON, INC. (US) 2023-09-26 US disclosed
WO-2023079206-A1 COMPOSITION WITH VIRUCIDAL ACTIVITY, USE AND APPLICATION METHOD THEREOF Bio Logic Crop Science S.L. (ES) 2023-05-11 WO disclosed
US-11452641-B2 Wound closure systems for reducing surgical site infections comprising incision drapes filled with releasable antimicrobial agents ETHICON, INC. (US) 2022-09-27 US disclosed
US-20220296423-A1 Wound Closure Systems for Reducing Surgical Site Infections Comprising Incision Drapes Filled with Releasable Antimicrobial Agents ETHICON, INC. (US) 2022-09-22 US disclosed
US-20220296422-A1 Wound Closure Systems for Reducing Surgical Site Infections Comprising Incision Drapes Filled with Releasable Antimicrobial Agents ETHICON, INC. (US) 2022-09-22 US disclosed
US-20040141922-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2004-07-22 US disclosed
US-6680047-B2 FOR USE IN ULTRASOUND IMAGING, CONTRAST AGENTS AMERSHAM HEALTH AS (NO) 2004-01-20 US disclosed
US-20020102215-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 US disclosed
US-20020102217-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 US disclosed
US-6331289-B1 ULTRASOUND CONTRAST AGENTS, SUSPENSION IN AQUEOUS CARRIER LIQUID OF A REPORTER COMPRISING GAS-CONTAINING OR GAS-GENERATING MATERIAL, AGENT CAPABLE OF FORMING AT LEAST TWO TYPES OF BINDING PAIRS WITH TARGET; REPORTER BEING CONJUGATED NYCOMED IMAGING AS (NO) 2001-12-18 US disclosed
US-6264917-B1 MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT NYCOMED IMAGING AS (NO) 2001-07-24 US disclosed
US-6261537-B1 TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES NYCOMED IMAGING AS (NO) 2001-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040141922-A1 Diagnostic/therapeutic agents BID, FUS, FABP1 ALDH1A1 4549/4885MAPT 1721/4885KMT2A 4460/4885
US-20250017879-A1 COMPOSITION WITH VIRUCIDAL ACTIVITY, USE AND APPLICATION THEREOF SARS1, ACE2, PHOSPHO1 ALDH1A1 2869/4885MAPT 336/4885KMT2A 1223/4885
US-20020102215-A1 Diagnostic/therapeutic agents BID, FUS, FABP1 ALDH1A1 4459/4885MAPT 2239/4885KMT2A 4411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.