Fosenazide

Fosenazide

SCHEMBL2109146

NNC(=O)CP(=O)(c1ccccc1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.62
POLB P06746 1/20 0.58
CYP2C9 P11712 1/20 0.57
NPSR1 Q6W5P4 3/20 0.51
HTT P42858 3/20 0.47
GAA P10253 3/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
ALDH1A1 P00352 3/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
MAPT P10636 5/20 0.44
HSD17B10 Q99714 1/20 0.44
ALPG P10696 1/20 0.44
ALOX12 P18054 1/20 0.44
NPY1R P25929 1/20 0.44
NPY2R P49146 1/20 0.44
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fosenazide SCHEMBL8843576 0.95 USP2 (0.72) USP2POLBCYP2C9NPSR1HTT
SCHEMBL22361763 0.78 USP2 (0.69) USP2POLBCYP2C9NPSR1HTT
SCHEMBL9009717 0.77 USP2 (1.00) USP2POLBCYP2C9NPSR1HTT
SCHEMBL13239817 0.74 USP2 (0.69) USP2POLBCYP2C9NPSR1HTT
SCHEMBL5076070 0.73 POLB (1.00) USP2POLBCYP2C9NPSR1HTT
SCHEMBL8843484 0.73 POLB (0.39) USP2POLBCYP2C9NPSR1HTT
SCHEMBL28971881 0.72 USP2 (0.67) USP2POLBCYP2C9NPSR1HTT
SCHEMBL3410872 0.72 GAA (0.67) USP2POLBNPSR1HTTGAA
SCHEMBL28663387 0.71 USP2 (0.64) USP2POLBCYP2C9NPSR1HTT
SCHEMBL28513732 0.71 USP2 (0.64) USP2POLBCYP2C9NPSR1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-4162264-A Process for preparing diphenylphosphinylacetic acid hydrazide NIKOLAEVA VALENTINA G (SU) 1979-07-24 US claimed
CN-119285674-A Synthesis method of fluoroalkyl N-acylhydrazone compound containing diphenyl phosphine oxide structural unit 西北师范大学 2025-01-10 CN disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-11191719-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2021-12-07 US disclosed
US-10463611-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2019-11-05 US disclosed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US disclosed
US-20140154313-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2014-06-05 US disclosed
US-6264917-B1 MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT NYCOMED IMAGING AS (NO) 2001-07-24 US disclosed
US-6261537-B1 TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES NYCOMED IMAGING AS (NO) 2001-07-17 US disclosed
US-5679663-A HYDRAZIDES OF PHOSPHINIC ACID DERIVATIVES; USED AS ANTI-DEPRESSANT AND MEMORY ENHANCEMENT BRITISH TECHNOLOGY GROUP LIMITED (GB) 1997-10-21 US disclosed
EP-0739347-A1 HYDRAZIDES OF PHOSPHORYLATED CARBOXYLIC ACIDS HAVING THERAPEUTIC ACTIVITY BTG INTERNATIONAL LIMITED (GB) 1996-10-30 EP disclosed
WO-1995018810-A1 HYDRAZIDES OF PHOSPHORYLATED CARBOXYLIC ACIDS HAVING THERAPEUTIC ACTIVITY BRITISH TECHNOLOGY GROUP LIMITED (GB) 1995-07-13 WO disclosed
US-4162264-A Process for preparing diphenylphosphinylacetic acid hydrazide NIKOLAEVA VALENTINA G (SU) 1979-07-24 US disclosed
US-4162264-A Process for preparing diphenylphosphinylacetic acid hydrazide NIKOLAEVA VALENTINA G (SU) 1979-07-24 US disclosed