Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fosenazide SCHEMBL2109146 | 0.95 | USP2 (0.62) | USP2POLBCYP2C9GAANPSR1 | |
| SCHEMBL9009717 | 0.85 | USP2 (1.00) | USP2POLBCYP2C9GAANPSR1 | |
| SCHEMBL22361763 | 0.74 | USP2 (0.69) | USP2POLBCYP2C9GAANPSR1 | |
| SCHEMBL13239817 | 0.70 | USP2 (0.69) | USP2POLBCYP2C9GAANPSR1 | |
| SCHEMBL5076070 | 0.69 | POLB (1.00) | USP2POLBCYP2C9GAANPSR1 | |
| SCHEMBL8843484 | 0.69 | POLB (0.39) | USP2POLBCYP2C9NPSR1HTT | |
| SCHEMBL9000877 | 0.69 | USP2 (0.68) | USP2POLBGAANPSR1HTT | |
| SCHEMBL28971881 | 0.68 | USP2 (0.67) | USP2POLBCYP2C9GAANPSR1 | |
| SCHEMBL3410872 | 0.68 | GAA (0.67) | USP2POLBGAANPSR1HTT | |
| SCHEMBL3948309 | 0.67 | USP2 (0.65) | USP2POLBGAANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679663-A | HYDRAZIDES OF PHOSPHINIC ACID DERIVATIVES; USED AS ANTI-DEPRESSANT AND MEMORY ENHANCEMENT | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1997-10-21 | — | — | US | disclosed |