Nonaperone

Nonaperone

SCHEMBL2109345

O=C(CCCN1CC2CCC(CC2)C1)c1ccc(F)cc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 2/20 0.67
MEN1 O00255 1/20 0.67
CHRM2 P08172 1/20 0.67
HTR1A P08908 1/20 0.67
ADRA2A P08913 1/20 0.67
DRD1 P21728 1/20 0.67
ADRA1A P35348 1/20 0.67
OPRM1 P35372 1/20 0.67
KMT2A Q03164 1/20 0.67
KCNH2 Q12809 1/20 0.67
HRH3 Q9Y5N1 1/20 0.67
DRD2 P14416 4/20 0.65
DRD4 P21917 1/20 0.65
TSHR P16473 1/20 0.62
KDM4E B2RXH2 1/20 0.60
HSD17B10 Q99714 1/20 0.60
CYP2D6 P10635 1/20 0.60
HTR2A P28223 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4501475 0.83 DRD3 (0.71) DRD3MEN1CHRM2HTR1AADRA2A
SCHEMBL10372093 0.82 DRD3 (0.60) DRD3MEN1CHRM2HTR1AADRA2A
SCHEMBL10370891 0.82 DRD3 (0.59) DRD3MEN1CHRM2HTR1AADRA2A
SCHEMBL10397519 0.81 DRD3 (0.58) DRD3MEN1CHRM2HTR1AADRA2A
SCHEMBL20254428 0.81 MEN1 (0.78) DRD3MEN1CHRM2HTR1AADRA2A
SCHEMBL4496558 0.80 TSHR (0.76) DRD3MEN1CHRM2HTR1AADRA2A
Melperone SCHEMBL146287 0.80 KMT2A (1.00) DRD3MEN1CHRM2HTR1AADRA2A
SCHEMBL11415059 0.80 MEN1 (0.76) DRD3MEN1CHRM2HTR1AADRA2A
Hydrochloric Acid SCHEMBL30658979 0.80 MEN1 (0.76) DRD3MEN1CHRM2HTR1AADRA2A
SCHEMBL5803445 0.80 DRD2 (0.57) DRD3MEN1CHRM2HTR1AADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3423033-A1 SELF-EMULSIFYING COMPOSITIONS OF CB2 RECEPTOR MODULATORS Anavi-Goffer, Sharon (IL) 2019-01-09 EP claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-11191719-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2021-12-07 US disclosed
US-10463611-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2019-11-05 US disclosed
EP-3423033-A1 SELF-EMULSIFYING COMPOSITIONS OF CB2 RECEPTOR MODULATORS Anavi-Goffer, Sharon (IL) 2019-01-09 EP disclosed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US disclosed
US-20140154313-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2014-06-05 US disclosed
US-20040141922-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2004-07-22 US disclosed
US-6680047-B2 FOR USE IN ULTRASOUND IMAGING, CONTRAST AGENTS AMERSHAM HEALTH AS (NO) 2004-01-20 US disclosed
US-20020102215-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 US disclosed
US-20020102217-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 US disclosed
US-6331289-B1 ULTRASOUND CONTRAST AGENTS, SUSPENSION IN AQUEOUS CARRIER LIQUID OF A REPORTER COMPRISING GAS-CONTAINING OR GAS-GENERATING MATERIAL, AGENT CAPABLE OF FORMING AT LEAST TWO TYPES OF BINDING PAIRS WITH TARGET; REPORTER BEING CONJUGATED NYCOMED IMAGING AS (NO) 2001-12-18 US disclosed
US-6264917-B1 MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT NYCOMED IMAGING AS (NO) 2001-07-24 US disclosed
US-6261537-B1 TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES NYCOMED IMAGING AS (NO) 2001-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040141922-A1 Diagnostic/therapeutic agents BID, FUS, FABP1 DRD3 4699/4885MEN1 410/4885CHRM2 4524/4885
US-20020102215-A1 Diagnostic/therapeutic agents BID, FUS, FABP1 DRD3 4723/4885MEN1 671/4885CHRM2 4525/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.