Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21093621 | 0.88 | ALDH1A1 (0.49) | ALDH1A1MAPK1HPGDCYP1A2CYP3A4 | |
| SCHEMBL21189138 | 0.87 | ALDH1A1 (0.46) | ALDH1A1MAPK1HPGDCYP1A2CYP3A4 | |
| SCHEMBL19851073 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MAPK1HPGDCYP1A2CYP3A4 | |
| SCHEMBL19851127 | 0.84 | SLC22A12 (0.45) | ALDH1A1MAPK1HPGDCYP1A2CYP3A4 | |
| SCHEMBL23954453 | 0.84 | ALDH1A1 (0.46) | ALDH1A1MAPK1HPGDCYP1A2CYP3A4 | |
| SCHEMBL19851102 | 0.84 | TSHR (0.52) | ALDH1A1MAPK1HPGDCYP1A2CYP3A4 | |
| SCHEMBL19851103 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MAPK1HPGDCYP1A2CYP3A4 | |
| SCHEMBL19851100 | 0.79 | TSHR (0.66) | ALDH1A1MAPK1HPGDCYP1A2CYP3A4 | |
| SCHEMBL21094240 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MAPK1HPGDCYP1A2CYP3A4 | |
| SCHEMBL19851108 | 0.79 | ALDH1A1 (0.40) | ALDH1A1MAPK1HPGDCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3495362-B1 | IMIDAZOPYRIDINE THIOGLYCOLIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | UNIV SHANDONG (CN) | 2021-10-27 | — | — | EP | disclosed |
| EP-3495362-A1 | IMIDAZOPYRIDINE THIOGLYCOLIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shandong University (CN) | 2019-06-12 | — | — | EP | disclosed |