Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CALCRL | Q16602 | 13/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21093556 | 0.89 | GPBAR1 (0.35) | PKM | |
| SCHEMBL21093969 | 0.88 | PKM (0.40) | PKMCALCRLRIPK1TMEM97SIGMAR1 | |
| SCHEMBL21093550 | 0.87 | PKM (0.40) | PKMCALCRLALDH1A1LMNA | |
| SCHEMBL21093785 | 0.87 | PKM (0.40) | PKMCALCRLRIPK1TMEM97SIGMAR1 | |
| SCHEMBL21093558 | 0.85 | PKM (0.38) | PKMCALCRLRIPK1TMEM97SIGMAR1 | |
| SCHEMBL21093985 | 0.82 | PKM (0.39) | PKMCALCRLALDH1A1LMNA | |
| SCHEMBL21093551 | 0.81 | CALCRL (0.42) | CALCRL | |
| SCHEMBL21093784 | 0.81 | PKM (0.38) | PKMCALCRLALDH1A1LMNA | |
| SCHEMBL20843354 | 0.77 | CALCRL (0.51) | CALCRLRIPK1 | |
| SCHEMBL20835515 | 0.77 | CALCRL (0.51) | CALCRLRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019112024-A1 | PYRROLIDINE COMPOUND | キッセイ薬品工業株式会社 | 2019-06-13 | — | — | WO | disclosed |