Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 11/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 5/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20565506 | 0.83 | KCNH2 (0.53) | KCNH2SCN3ARIPK1CA1 | |
| SCHEMBL2040118 | 0.83 | KCNH2 (0.53) | KCNH2SCN3ARIPK1CA1 | |
| SCHEMBL20565520 | 0.83 | KCNH2 (0.53) | KCNH2SCN3ARIPK1CA1 | |
| SCHEMBL12318222 | 0.83 | KCNH2 (0.50) | KCNH2SCN3ASCN9A | |
| SCHEMBL31479382 | 0.81 | KCNH2 (0.52) | KCNH2SCN3ARIPK1CA1 | |
| SCHEMBL5515868 | 0.81 | KCNH2 (0.52) | KCNH2SCN3ARIPK1CA1 | |
| SCHEMBL24220439 | 0.78 | KCNH2 (0.49) | KCNH2SCN3ATDP1 | |
| SCHEMBL20835748 | 0.78 | KCNH2 (0.49) | KCNH2SCN3ATDP1 | |
| SCHEMBL21094396 | 0.74 | RIPK1 (0.39) | KCNH2SCN3ARIPK1TDP1 | |
| SCHEMBL20835922 | 0.74 | KCNH2 (0.38) | KCNH2SCN3ARIPK1TDP1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019112024-A1 | PYRROLIDINE COMPOUND | キッセイ薬品工業株式会社 | 2019-06-13 | — | — | WO | disclosed |