Alepride

Alepride

SCHEMBL2109370

C=CCOc1cc(N)c(Cl)cc1C(=O)NC1CCN(CC2CC=CCC2)CC1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MLNR O43193 1/20 0.62
ADRB2 P07550 1/20 0.62
CHRM1 P11229 1/20 0.62
DRD2 P14416 1/20 0.62
ADRA2B P18089 1/20 0.62
ADRA2C P18825 1/20 0.62
CHRM3 P20309 1/20 0.62
SLC6A2 P23975 1/20 0.62
HTR2A P28223 1/20 0.62
SLC6A4 P31645 1/20 0.62
HRH1 P35367 1/20 0.62
DRD3 P35462 1/20 0.62
OPRK1 P41145 1/20 0.62
HTR2B P41595 1/20 0.62
CHRNA4 P43681 1/20 0.62
HTR3A P46098 1/20 0.62
SLC6A3 Q01959 1/20 0.62
KCNH2 Q12809 1/20 0.62
HRH3 Q9Y5N1 1/20 0.62
HTR4 Q13639 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11545402 0.88 HTR4 (0.59) HTR4
Hydrochloric Acid SCHEMBL11547472 0.87 HTR4 (0.58) HTR4
SCHEMBL9865727 0.87 MLNR (0.82) MLNRADRB2CHRM1DRD2ADRA2B
SCHEMBL11946697 0.80 MLNR (0.77) MLNRADRB2CHRM1DRD2ADRA2B
SCHEMBL19235643 0.79 MLNR (0.86) MLNRADRB2CHRM1DRD2ADRA2B
SCHEMBL11546300 0.79 DRD4 (0.54) DRD2ADRA2BADRA2CSLC6A2HTR2A
Hydrochloric Acid SCHEMBL11548359 0.78 DRD4 (0.53) DRD2ADRA2BADRA2CSLC6A2HTR2A
SCHEMBL11547502 0.77 HTR4 (0.70) HTR4
Cinitapride SCHEMBL29453925 0.76 MLNR (1.00) MLNRADRB2CHRM1DRD2ADRA2B
SCHEMBL13453078 0.76 MLNR (0.71) MLNRADRB2CHRM1DRD2ADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
CN-112739717-B Trispecific antagonists 璟尚生物制药公司 2025-02-11 CN disclosed
CN-112601751-B Fused thiophene compounds 拜欧斯瑞克斯公司 2024-04-02 CN disclosed
CN-116940351-A Prodrug compositions and methods of treatment 阿奎斯蒂弗医疗股份有限公司 2023-10-24 CN disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-11191719-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2021-12-07 US disclosed
US-10463611-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2019-11-05 US disclosed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US disclosed
US-20040141922-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2004-07-22 US disclosed
US-6680047-B2 FOR USE IN ULTRASOUND IMAGING, CONTRAST AGENTS AMERSHAM HEALTH AS (NO) 2004-01-20 US disclosed
US-20020102215-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 US disclosed
US-20020102217-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 US disclosed
US-6331289-B1 ULTRASOUND CONTRAST AGENTS, SUSPENSION IN AQUEOUS CARRIER LIQUID OF A REPORTER COMPRISING GAS-CONTAINING OR GAS-GENERATING MATERIAL, AGENT CAPABLE OF FORMING AT LEAST TWO TYPES OF BINDING PAIRS WITH TARGET; REPORTER BEING CONJUGATED NYCOMED IMAGING AS (NO) 2001-12-18 US disclosed
US-6264917-B1 MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT NYCOMED IMAGING AS (NO) 2001-07-24 US disclosed
US-6261537-B1 TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES NYCOMED IMAGING AS (NO) 2001-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040141922-A1 Diagnostic/therapeutic agents BID, FUS, FABP1 MLNR 2893/4885ADRB2 1875/4885CHRM1 4575/4885
US-20020102215-A1 Diagnostic/therapeutic agents BID, FUS, FABP1 MLNR 2754/4885ADRB2 2022/4885CHRM1 4583/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.