SCHEMBL21094666

SCHEMBL21094666

c1ccc(-c2ccc(N(c3ccc4c(c3)C3(c5ccccc5-c5ccccc53)c3ccccc3-4)c3cccc4oc5ccccc5c34)cc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.32
PLA2G2A P14555 2/20 0.31
PLA2G4A P47712 2/20 0.31
ALOX5 P09917 1/20 0.30
TNKS O95271 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19168748 0.99 PDK2 (0.31) PDK2PLA2G2APLA2G4AALOX5
SCHEMBL19166138 0.99 PDK2 (0.31) PDK2PLA2G2APLA2G4AALOX5
SCHEMBL21094810 0.98 PDK2 (0.35) PDK2PLA2G2APLA2G4A
SCHEMBL21095297 0.98 PDK2 (0.35) PDK2PLA2G2APLA2G4A
SCHEMBL25563359 0.98 PDK2 (0.30) PDK2PLA2G2APLA2G4A
SCHEMBL21094805 0.97 PDK2 (0.34) PDK2PLA2G2APLA2G4A
SCHEMBL21095298 0.97 PDK2 (0.34) PDK2PLA2G2APLA2G4A
SCHEMBL21559336 0.96 TNKS (0.30) TNKS
SCHEMBL21094630 0.96 PDK2 (0.32) PDK2PLA2G2APLA2G4AALOX5TNKS
SCHEMBL21559338 0.95

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190185460-A1 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2019-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190185460-A1 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME AOC2, TYR, MAOB PDK2 2385/4885PLA2G2A 3782/4885PLA2G4A 4099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.