Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 19/20 | 0.72 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2606783 | 1.00 | PYGL (0.72) | PYGLMMP9MMP8MMP14 | |
| SCHEMBL13271509 | 0.84 | PYGL (0.50) | PYGL | |
| SCHEMBL2606772 | 0.84 | PYGL (0.73) | PYGLMMP9MMP8MMP14 | |
| SCHEMBL2107248 | 0.84 | PYGL (0.73) | PYGLMMP9MMP8MMP14 | |
| SCHEMBL2108895 | 0.84 | PYGL (0.72) | PYGL | |
| SCHEMBL2606801 | 0.84 | PYGL (0.72) | PYGL | |
| SCHEMBL2606774 | 0.82 | PYGL (0.70) | PYGL | |
| SCHEMBL2107202 | 0.82 | PYGL (0.70) | PYGL | |
| SCHEMBL2606758 | 0.81 | PYGL (0.74) | PYGL | |
| SCHEMBL2107329 | 0.81 | PYGL (0.74) | PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158622-B2 | Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase | PROSIDION LIMITED (GB) | 2012-04-17 | — | — | US | disclosed |