Etisazole

Etisazole

SCHEMBL2109479

CCNc1nsc2ccccc12

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPAS1 Q99814 9/20 0.56
ACHE P22303 1/20 0.47
EPHX2 P34913 1/20 0.46
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HSD17B10 Q99714 1/20 0.46
UTS2R Q9UKP6 1/20 0.40
CYP1A1 P04798 2/20 0.38
CYP1A2 P05177 2/20 0.38
TP53 P04637 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
IDO1 P14902 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Etisazole SCHEMBL30496100 1.00 EPAS1 (0.56) EPAS1ACHEEPHX2MAPTKDM4E
SCHEMBL13202776 0.85 EPAS1 (0.59) EPAS1ACHEEPHX2MAPTKDM4E
SCHEMBL3854234 0.82 SMN1; SMN2 (0.51) EPAS1ACHEUTS2RSMN1; SMN2
SCHEMBL13202796 0.81 EPAS1 (0.56) EPAS1ACHEEPHX2MAPTKDM4E
SCHEMBL2977289 0.79 EPAS1 (0.53) EPAS1ACHEEPHX2MAPTKDM4E
SCHEMBL11443229 0.79 EPAS1 (0.61) EPAS1ACHEEPHX2MAPTKDM4E
SCHEMBL21336655 0.77 EPAS1 (0.65) EPAS1ACHEEPHX2MAPTKDM4E
SCHEMBL9066324 0.77 EPAS1 (0.51) EPAS1ACHEEPHX2MAPTKDM4E
SCHEMBL6108893 0.76 EPAS1 (0.50) EPAS1ACHEEPHX2MAPTKDM4E
SCHEMBL7378228 0.76 EPAS1 (0.33) EPAS1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11534375-B2 Solvent-free method of encapsulating a hydrophobic active AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2022-12-27 US claimed
US-20200179248-A1 SOLVENT-FREE METHOD OF ENCAPSULATING A HYDROPHOBIC ACTIVE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2020-06-11 US claimed
WO-2018182509-A1 SOLVENT-FREE METHOD OF ENCAPSULATING A HYDROPHOBIC ACTIVE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2018-10-04 WO claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
CN-103923765-A Detergent Composition For Process Of Manufacturing Semiconductors And Displays COWON INNOTECH INC 2014-07-16 CN claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20030007826-A1 Adhesive treatment for tinea pedis CLOSURE MEDICAL CORPORATION 2003-01-09 US claimed
US-20030007947-A1 Adhesive treatment for oral fungal infection CLOSURE MEDICAL CORPORATION (US) 2003-01-09 US claimed
US-20030007946-A1 Adhesive treatment for tinea cruris CLOSURE MEDICAL CORPORATION (US) 2003-01-09 US claimed
US-20030007948-A1 Adhesive treatment for skin yeast infections CLOSURE MEDICAL CORPORATION (US) 2003-01-09 US claimed
US-20030007949-A1 Adhesive treatment for tinea corporis CLOSURE MEDICAL CORPORATION (US) 2003-01-09 US claimed
EP-0687172-B1 SOLID LIPID PARTICLES, PARTICLES OF BIOACTIVE AGENTS AND METHODS FOR THE MANUFACTURE AND USE THEREOF PHARMACIA AB (SE) 2002-12-04 EP claimed
US-6207178-B1 STABLE SUSPENSION KABI PHARMACIA AB (SE) 2001-03-27 US claimed
US-5785976-A Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof PHARMACIA & UPJOHN AB (SE) 1998-07-28 US claimed
EP-0687172-A1 SOLID LIPID PARTICLES, PARTICLES OF BIOACTIVE AGENTS AND METHODS FOR THE MANUFACTURE AND USE THEREOF Pharmacia & Upjohn Aktiebolag (SE) 1995-12-20 EP claimed
WO-1994020072-A1 SOLID LIPID PARTICLES, PARTICLES OF BIOACTIVE AGENTS AND METHODS FOR THE MANUFACTURE AND USE THEREOF PHARMACIA AB (SE) 1994-09-15 WO claimed