SCHEMBL21095368

SCHEMBL21095368

Cc1ccc(C(NC(=O)C[C@H](N)C(=O)O)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 15/20 0.57
SLC1A3 P43003 5/20 0.46
SLC1A2 P43004 5/20 0.46
SLC1A1 P43005 5/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17477557 0.91 SLC1A3 (0.53) KIF11SLC1A3SLC1A2SLC1A1
SCHEMBL25209459 0.91 SLC1A3 (0.53) KIF11SLC1A3SLC1A2SLC1A1
SCHEMBL21690461 0.91 SLC1A3 (0.53) KIF11SLC1A3SLC1A2SLC1A1
Water SCHEMBL29400657 0.90 SLC1A3 (0.51) KIF11SLC1A3SLC1A2SLC1A1
SCHEMBL21096128 0.86 KIF11 (0.61) KIF11
SCHEMBL29493130 0.85 KIF11 (0.60) KIF11SLC1A3SLC1A2SLC1A1
SCHEMBL8358733 0.82 KIF11 (0.41) KIF11SLC1A3SLC1A2SLC1A1
SCHEMBL29516472 0.81 KIF11 (0.61) KIF11
SCHEMBL30918354 0.81 KIF11 (0.41) KIF11SLC1A3SLC1A2SLC1A1
SCHEMBL8227058 0.80 KIF11 (0.49) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240200049-A1 COMPOSITIONS AND METHODS OF USE THEREOF FOR MAKING POLYPEPTIDES WITH MANY INSTANCES OF NONSTANDARD AMINO ACIDS YALE UNIVERSITY 2024-06-20 US disclosed
US-11649446-B2 Compositions and methods of use thereof for making polypeptides with many instances of nonstandard amino acids YALE UNIVERSITY (US) 2023-05-16 US disclosed
WO-2019115609-A1 SACCHARIDE FUNCTIONALISED CARBABORANE CONJUGATES OF HUMAN PEPTIDE Y UNIVERSITÄT LEIPZIG (DE) 2019-06-20 WO disclosed