Aliconazole

Aliconazole

SCHEMBL2109609

Clc1ccc(C(=Cc2ccc(Cl)cc2Cl)Cn2ccnc2)cc1

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.47
ADRA2C P18825 2/20 0.47
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA3 P07451 1/20 0.45
CA4 P22748 1/20 0.45
CA6 P23280 1/20 0.45
CA5A P35218 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
CA13 Q8N1Q1 1/20 0.45
CA14 Q9ULX7 1/20 0.45
CA5B Q9Y2D0 1/20 0.45
CYP2A6 P11509 1/20 0.44
CYP11B1 P15538 1/20 0.44
CYP11B2 P19099 1/20 0.44
CYP2B6 P20813 1/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2D6 P10635 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aliconazole SCHEMBL2109608 1.00 CYP19A1 (0.47) CYP19A1ADRA2CCA12CA1CA2
Aliconazole SCHEMBL29532590 1.00 CYP19A1 (0.47) CYP19A1ADRA2CCA12CA1CA2
SCHEMBL11719546 0.93 CYP19A1 (0.47) CYP19A1ADRA2CCA12CA1CA2
SCHEMBL2355400 0.90 CYP19A1 (0.46) CYP19A1ADRA2CCA12CA1CA2
SCHEMBL2355395 0.90 CYP19A1 (0.46) CYP19A1ADRA2CCA12CA1CA2
SCHEMBL2355399 0.90 CYP19A1 (0.46) CYP19A1ADRA2CCA12CA1CA2
SCHEMBL11722279 0.88 CYP3A4 (0.52) CYP19A1ADRA2CCA12CA1CA2
Ethylene Glycol SCHEMBL11038393 0.84 CYP3A4 (0.49) CYP19A1ADRA2CCA12CA1CA2
SCHEMBL11724328 0.83 CYP19A1 (0.59) CYP19A1CYP2A6CYP11B1CYP11B2CYP2B6
SCHEMBL11723422 0.80 CYP19A1 (0.62) CYP19A1CYP2A6CYP11B1CYP11B2CYP2B6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20040254182-A1 Enhanced propertied pharmaceuticals ROHM AND HAAS COMPANY 2004-12-16 US claimed
CN-1441790-A Enhanced propertied pharmaceuticals ROHM & HAAS (US) 2003-09-10 CN claimed
EP-1272463-A1 ENHANCED PROPERTIED PHARMACEUTICALS ROHM AND HAAS COMPANY (US) 2003-01-08 EP claimed
WO-2001054481-A2 ENHANCED PROPERTIED PHARMACEUTICALS ROHM AND HAAS COMPANY (US) 2001-08-02 WO claimed
US-4057545-A FUNGICIDE, BACTERICIDE NORDMARK-WERKE GMBH HAMBURG (DT) 1977-11-08 US claimed
US-20240226067-A9 ANTI-FIBROTIC THERAPIES THE JOHNS HOPKINS UNIVERSITY 2024-07-11 US disclosed
US-20240131006-A1 ANTI-FIBROTIC THERAPIES UNIV JOHNS HOPKINS (US) 2024-04-25 US disclosed
WO-2022187287-A1 ANTI-FIBROTIC THERAPIES THE JOHNS HOPKINS UNIVERSITY (US) 2022-09-09 WO disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-6261537-B1 TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES NYCOMED IMAGING AS (NO) 2001-07-17 US disclosed
EP-0719552-A2 Pharmaceutical composition comprising a quinone derivative or a hydroquinone thereof for treating dermatitis Takeda Chemical Industries, Ltd. (JP) 1996-07-03 EP disclosed
US-4894375-A FUNGISTATS, KETOCONAZOLE MERCK & CO., INC. (US) 1990-01-16 US disclosed
US-4871741-A FUNGICIDES; KETOCONAZOLE AND MEVINOLINIC ACID MERCK & CO., INC. (US) 1989-10-03 US disclosed
US-4782059-A Method of controlling mycotic infections and compositions therefor MERCK & CO., INC. (US) 1988-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040254182-A1 Enhanced propertied pharmaceuticals ABCB1, ABCB11, ABCG2 CYP19A1 946/4885ADRA2C 1822/4885CA12 2325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.