SCHEMBL210975

SCHEMBL210975

C=COC(=O)/C(C#N)=C(\c1ccccc1)c1ccc(CC)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
LMNA P02545 3/20 0.46
MAPK1 P28482 2/20 0.46
RAB9A P51151 4/20 0.36
MAPT P10636 3/20 0.36
NPSR1 Q6W5P4 2/20 0.36
XBP1 P17861 1/20 0.36
TP53 P04637 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
SMN1; SMN2 Q16637 4/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 1/20 0.35
HPGD P15428 1/20 0.35
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
CYP3A4 P08684 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
NPC1 O15118 2/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL210976 1.00 ALDH1A1 (0.46) ALDH1A1LMNAMAPK1RAB9AMAPT
SCHEMBL9068112 0.88 ALDH1A1 (0.46) ALDH1A1LMNAMAPK1RAB9AMAPT
SCHEMBL10900961 0.75 ALDH1A1 (0.52) ALDH1A1LMNAMAPK1RAB9AMAPT
Etocrylene SCHEMBL39390 0.74 ALDH1A1 (0.62) ALDH1A1LMNAMAPK1RAB9AMAPT
Etocrylene SCHEMBL1768864 0.74 ALDH1A1 (0.62) ALDH1A1LMNAMAPK1RAB9AMAPT
SCHEMBL24703978 0.74 ALDH1A1 (0.50) ALDH1A1LMNAMAPK1RAB9AMAPT
SCHEMBL8999069 0.73 ALDH1A1 (0.53) ALDH1A1LMNAMAPK1RAB9AMAPT
SCHEMBL8999061 0.73 ALDH1A1 (0.53) ALDH1A1LMNAMAPK1RAB9AMAPT
SCHEMBL521197 0.73 ALDH1A1 (0.52) ALDH1A1LMNAMAPK1RAB9AMAPT
Etocrylene SCHEMBL4076085 0.73 ALDH1A1 (0.61) ALDH1A1LMNAMAPK1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230257573-A1 COMPOSITION INCLUDING AN ACRYLIC POLYMER, A WATER-REPELLENT POLYMER, AND AN ULTRAVIOLET LIGHT STABILIZER AND RELATED ARTICLES AND METHODS 3M INNOVATIVE PROPERTIES COMPANY 2023-08-17 US disclosed
EP-3157988-B1 LIGHT TRANSPARENT FLUOROPOLYMER COMPOSITION AND ARTICLE 3M INNOVATIVE PROPERTIES CO (US) 2021-12-01 EP disclosed
US-11110689-B2 Pressure sensitive adhesive composition including ultraviolet light-absorbing oligomer 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-09-07 US disclosed
US-10836883-B2 Light transparent fluoropolymer composition and article 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-11-17 US disclosed
EP-3313906-B1 COPOLYMER INCLUDING ULTRAVIOLET LIGHT-ABSORBING GROUP AND COMPOSITIONS INCLUDING THE SAME 3M INNOVATIVE PROPERTIES CO (US) 2020-08-05 EP disclosed
EP-3161078-B1 EXTRUDED FILM COMPRISING A FLUOROPOLYMER COMPOSITION INCLUDING AT LEAST ONE OLIGOMER 3M INNOVATIVE PROPERTIES CO (US) 2020-05-27 EP disclosed
US-10577467-B2 Fluoropolymer composition including an oligomer having an ultraviolet absorbing group 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-03-03 US disclosed
CN-106459545-B Light transmission fluoro-containing copolymer composition and product 3M创新有限公司 2019-12-03 CN disclosed
CN-105073909-B Fluoropolymer composition comprising oligomers having ultraviolet absorbing groups 3M创新有限公司 2019-05-21 CN disclosed
CN-106661365-B Fluoropolymer composition comprising at least one oligomer 3M创新有限公司 2019-03-01 CN disclosed
CN-103348192-A Novel solar concentration device EVONIK ROEHM GMBH 2013-10-09 CN disclosed
US-8088847-B2 Surface protective coating for polyvinyl chloride window; molding materials blend containing radiation transparent plastic and ultraviolet radiation stabilizer and absorber EVONIK ROEHM GMBH (DE) 2012-01-03 US disclosed
US-20100189983-A1 PMMA/PVDF FILM WITH PARTICULARLY HIGH WEATHERING STABILITY AND HIGH UV PROTECTIVE ACTION EVONIK ROEHM GMBH (DE) 2010-07-29 US disclosed
US-7754317-B2 Weather-resistant film for the yellow coloration of retro-reflective moulded bodies EVONIK ROEHM GMBH (DE) 2010-07-13 US disclosed
CN-101730717-A Pmma/pvdf film with particularly high weathering stability and high uv protective action EVONIK ROEHM GMBH 2010-06-09 CN disclosed
CN-1930218-B Weather-resistant film for yellow-coloring retroreflective molded articles ROEHM GMBH 2010-05-05 CN disclosed
US-20080281023-A1 Pmma Film Featuring Particularly Great Weather Resistance and Great Uv Protection EVONIK ROEHM GMBH (DE) 2008-11-13 US disclosed
US-20070197703-A1 Weather-Resistant Film For The Yellow Coloration Of Retro-Reflective Moulded Bodies ROEHM GMBH (DE) 2007-08-23 US disclosed
CN-1930218-A Weather-resistant film for yellow-coloring retroreflective molded articles ROEHM GMBH (DE) 2007-03-14 CN disclosed
US-5449557-A Protective coatings for plastics, ultraviolet radiation resistance, polycarbonate, polyvinyl chloride or polyvinylidene fluoride and acrylic ester or amide polymer ROHM GMBH (DE) 1995-09-12 US disclosed