Nitroclofene

Nitroclofene

SCHEMBL2109767

O=[N+]([O-])c1cc(Cl)c(O)c(Cc2cc(Cl)cc([N+](=O)[O-])c2O)c1

nearest known ligand 0.62

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 5/20 0.62
ALDH1A1 P00352 5/20 0.45
HSD17B10 Q99714 3/20 0.45
TTR P02766 2/20 0.45
MEN1 O00255 2/20 0.45
MAPT P10636 2/20 0.45
KMT2A Q03164 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
HPGD P15428 2/20 0.45
CYP1A2 P05177 2/20 0.45
CYP2C9 P11712 2/20 0.45
KDM4E B2RXH2 1/20 0.45
ALOX15 P16050 1/20 0.45
ALOX12 P18054 1/20 0.45
MAPK1 P28482 1/20 0.45
RECQL P46063 1/20 0.45
PMP22 Q01453 1/20 0.45
HIF1A Q16665 1/20 0.45
HSP90AA1 P07900 1/20 0.44
SNCA P37840 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitroclofene SCHEMBL29540074 1.00 GPR35 (0.62) GPR35ALDH1A1HSD17B10TTRMEN1
SCHEMBL68720 0.88 GPR35 (0.62) GPR35ALDH1A1HSD17B10TTRMEN1
SCHEMBL11007373 0.88 GPR35 (0.52) GPR35ALDH1A1HSD17B10TTRMEN1
SCHEMBL11330105 0.86 GPR35 (0.50) GPR35ALDH1A1HSD17B10TTRMEN1
SCHEMBL68433 0.83 GPR35 (0.63) GPR35ALDH1A1HSD17B10TTRMEN1
SCHEMBL19419866 0.79 GPR35 (0.59) GPR35ALDH1A1HSD17B10TTRMEN1
SCHEMBL16181312 0.78 HIF1A (0.66) GPR35ALDH1A1HSD17B10TTRMEN1
SCHEMBL30807397 0.78 GPR35 (1.00) GPR35ALDH1A1HSD17B10TTRMEN1
SCHEMBL2165473 0.78 GPR35 (1.00) GPR35ALDH1A1HSD17B10TTRMEN1
SCHEMBL19425414 0.77 MEN1 (0.46) GPR35ALDH1A1HSD17B10TTRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106499148-A Composite decorating board 重庆中技万彩世界实业有限公司 2017-03-15 CN claimed
CN-106070004-A The cultural method of ecological goat 蔡永光 2016-11-09 CN claimed
CN-104542458-B A kind of ecological cultivation method of boer goat 马鞍山市金农牧业有限公司 2016-10-12 CN claimed
CN-104488819-B A kind of high-yield cultivation method of Yangze river and Huai river Small-xiang goat 马鞍山市金农牧业有限公司 2016-10-12 CN claimed
CN-105213337-A Albendazole dispersible tablet for animals and preparation method thereof SICHUAN CHENGBANG PHARMACEUTICAL CO LTD 2016-01-06 CN claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101703776-A Method for preparing anti-infective agent long-acting injection LUOYANG HUIZHONG ANIMAL MEDICI 2010-05-12 CN claimed
CN-101664417-A Niclofolan-contained compound sustained-release animal parasiticide WUWEI HONGNIU AGRICULTURAL & A 2010-03-10 CN claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-4296131-A DIMETHYL SULFOXIDE, ADIPIC ACID ESTER SOLVENT VEHICLES ACF CHEMIEFARMA N.V. (NL) 1981-10-20 US claimed
EP-0003382-A1 Solvent vehicle for therapeutics and pharmaceutical composition containing it ACF CHEMIEFARMA NV (NL) 1979-08-08 EP claimed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-10463611-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2019-11-05 US disclosed
US-4205089-A DIALKYL ESTER OF ADIPIC ACID AND DIMETHYL SULFOXIDE ACF CHEMIEFARMA N.V. (NL) 1980-05-27 US disclosed
EP-0003382-A1 Solvent vehicle for therapeutics and pharmaceutical composition containing it ACF CHEMIEFARMA NV (NL) 1979-08-08 EP disclosed
EP-0003382-A1 Solvent vehicle for therapeutics and pharmaceutical composition containing it ACF CHEMIEFARMA NV (NL) 1979-08-08 EP disclosed