SCHEMBL21097733

SCHEMBL21097733

CC(C)[C@@H](C)NC(=O)CCCC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
FAAH O00519 2/20 0.40
MAPK1 P28482 1/20 0.40
ASAH2 Q9NR71 1/20 0.36
ALDH1A1 P00352 3/20 0.36
ASAH1 Q13510 1/20 0.36
ACER2 Q5QJU3 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.34
GAA P10253 1/20 0.34
HPGD P15428 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
DNM1 Q05193 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20644803 0.94 FAAH (0.43) MEN1KMT2AFAAHMAPK1ASAH2
SCHEMBL20644804 0.93 FAAH (0.46) MEN1KMT2AFAAHMAPK1ASAH2
SCHEMBL17231647 0.93 FAAH (0.46) MEN1KMT2AFAAHMAPK1ASAH2
SCHEMBL18541216 0.84 MEN1 (0.57) MEN1KMT2AFAAHMAPK1ALDH1A1
SCHEMBL23521094 0.79 FAAH (0.43) MEN1KMT2AFAAHMAPK1ASAH2
SCHEMBL23913185 0.79 SMN1; SMN2 (0.34) ALDH1A1SMN1; SMN2GAAHPGDNPSR1
SCHEMBL8298120 0.78 FAAH (0.59) MEN1KMT2AFAAHMAPK1ASAH2
SCHEMBL9158547 0.77 FAAH (0.63) MEN1KMT2AFAAHMAPK1ASAH2
SCHEMBL9738234 0.77 FAAH (0.63) MEN1KMT2AFAAHMAPK1ASAH2
SCHEMBL9150544 0.77 FAAH (0.63) MEN1KMT2AFAAHMAPK1ASAH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10716801-B2 Silanol based therapeutic payloads BLINKBIO, INC. (US) 2020-07-21 US disclosed
US-20190183913-A1 Silanol Based Therapeutic Payloads BLINKBIO INC (US) 2019-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190183913-A1 Silanol Based Therapeutic Payloads CD47, CD4, BST2 MEN1 2446/4885KMT2A 2014/4885FAAH 3066/4885
US-10716801-B2 Silanol based therapeutic payloads CD47, CD4, BST2 MEN1 2446/4885KMT2A 2014/4885FAAH 3066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.