Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.36 |
| ▸ | RARA | P10276 | 2/20 | 0.35 |
| ▸ | RARB | P10826 | 2/20 | 0.35 |
| ▸ | RARG | P13631 | 2/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 5/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.34 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.34 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21097776 | 0.95 | SLC6A9 (0.35) | PTPN11RARARARBRARGSLC6A9 | |
| SCHEMBL21097762 | 0.94 | SLC6A9 (0.37) | RARARARBRARGSLC6A9PPARD | |
| SCHEMBL20288602 | 0.93 | MAPK1 (0.34) | PTPN11RARARARBRARGPPARD | |
| SCHEMBL21097783 | 0.92 | SLC6A9 (0.36) | RARARARBRARGSLC6A9PPARD | |
| SCHEMBL17070540 | 0.92 | CNR2 (0.36) | PTPN11RARARARBRARGPPARD | |
| SCHEMBL18646503 | 0.92 | CNR2 (0.36) | PTPN11RARARARBRARGPPARD | |
| SCHEMBL18646493 | 0.91 | CNR2 (0.37) | PTPN11RARBPPARDCNR2CNR1 | |
| SCHEMBL21097825 | 0.89 | MAPK1 (0.34) | RARARARBRARGPPARDPPARG | |
| SCHEMBL21097828 | 0.89 | MAPK1 (0.34) | RARARARBRARGPPARDPPARG | |
| SCHEMBL18646506 | 0.89 | CNR2 (0.36) | PTPN11RARARARBRARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11072742-B2 | Liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2021-07-27 | — | — | US | disclosed |
| US-20190185754-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2019-06-20 | — | — | US | disclosed |