Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 3/20 | 0.40 |
| ▸ | STS | P08842 | 6/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21063761 | 0.86 | NR1H2 (0.46) | NR1H2SCN9ANAMPTSTSGPR119 | |
| SCHEMBL19151669 | 0.82 | NR1H2 (0.53) | NR1H2NAMPTGLS | |
| SCHEMBL24392549 | 0.82 | NR1H2 (0.56) | NR1H2NAMPTGLS | |
| SCHEMBL2300227 | 0.81 | NR1H2 (0.51) | NR1H2NAMPTGLS | |
| SCHEMBL23003379 | 0.79 | NAMPT (0.51) | NR1H2SCN9ANAMPTSTSGPR119 | |
| SCHEMBL18497323 | 0.79 | NR1H2 (0.50) | NR1H2NAMPTGLSGPR119 | |
| SCHEMBL21097919 | 0.79 | DGAT1 (0.33) | — | |
| SCHEMBL14258986 | 0.78 | EPHX1 (0.49) | NR1H2NAMPTGLS | |
| SCHEMBL3595487 | 0.78 | STS (0.65) | NR1H2NAMPTSTSGPR119 | |
| SCHEMBL21805919 | 0.77 | NR1H2 (0.54) | NR1H2NAMPTGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019118612-A1 | TARGETING COMPOUNDS | ZAFGEN, INC. (US) | 2019-06-20 | — | — | WO | disclosed |