Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21098138 | 1.00 | KDM4E (0.33) | KDM4EALDH1A1POLBLMNAHTT | |
| SCHEMBL21582884 | 1.00 | KDM4E (0.33) | KDM4EALDH1A1POLBLMNAHTT | |
| SCHEMBL13719963 | 0.77 | — | — | |
| SCHEMBL21098386 | 0.77 | — | — | |
| SCHEMBL10268948 | 0.68 | KDM4E (0.46) | KDM4EALDH1A1POLBLMNAHTT | |
| SCHEMBL11501519 | 0.68 | KDM4E (0.46) | KDM4EALDH1A1POLBLMNAHTT | |
| SCHEMBL21727237 | 0.68 | KDM4E (0.46) | KDM4EALDH1A1POLBLMNAHTT | |
| SCHEMBL11501520 | 0.68 | KDM4E (0.46) | KDM4EALDH1A1POLBLMNAHTT | |
| SCHEMBL2904322 | 0.68 | KDM4E (0.46) | KDM4EALDH1A1POLBLMNAHTT | |
| SCHEMBL12909388 | 0.68 | KDM4E (0.46) | KDM4EALDH1A1POLBLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019118612-A1 | TARGETING COMPOUNDS | ZAFGEN, INC. (US) | 2019-06-20 | — | — | WO | disclosed |