Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 8/20 | 0.41 |
| ▸ | HTR2A | P28223 | 7/20 | 0.41 |
| ▸ | HTR2B | P41595 | 7/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BRD1 | O95696 | 1/20 | 0.39 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21098716 | 1.00 | KDR (0.46) | KDRRAD52HTR2CHTR2AHTR2B | |
| SCHEMBL19709333 | 1.00 | KDR (0.46) | KDRRAD52HTR2CHTR2AHTR2B | |
| SCHEMBL19709302 | 0.85 | HTR2C (0.42) | RAD52HTR2CHTR2AHTR2BBRPF1 | |
| SCHEMBL5630952 | 0.84 | RAD52 (0.49) | RAD52HTR2CHTR2AHTR2B | |
| SCHEMBL5632465 | 0.84 | RAD52 (0.49) | RAD52HTR2CHTR2AHTR2B | |
| SCHEMBL5630960 | 0.84 | RAD52 (0.49) | RAD52HTR2CHTR2AHTR2B | |
| SCHEMBL21461789 | 0.84 | ADAMTS5 (0.45) | RAD52HTR2CHTR2AHTR2BALK | |
| SCHEMBL19709537 | 0.84 | ADAMTS5 (0.45) | RAD52HTR2CHTR2AHTR2BALK | |
| SCHEMBL1639581 | 0.84 | HTR2C (0.48) | RAD52HTR2CHTR2AHTR2BSLC6A2 | |
| SCHEMBL1639678 | 0.84 | HTR2C (0.48) | RAD52HTR2CHTR2AHTR2BSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3498715-B1 | ANTI-HCMV VIRUS COMPOUND | MEDSHINE DISCOVERY INC (CN) | 2021-06-09 | — | — | EP | disclosed |
| EP-3498715-A1 | ANTI-HCMV VIRUS COMPOUND | Medshine Discovery Inc. (CN) | 2019-06-19 | — | — | EP | disclosed |