Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 10/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21052036 | 0.83 | PPARD (0.74) | PPARDMAOBHPGDALDH1A1 | |
| SCHEMBL21098733 | 0.82 | LMNA (0.48) | PPARDMAOBLMNAKDM4EMAPT | |
| SCHEMBL3660001 | 0.80 | PPARD (0.57) | PPARDMAOBALDH1A1 | |
| SCHEMBL10687936 | 0.78 | PPARD (0.71) | PPARDMAOB | |
| SCHEMBL12173365 | 0.76 | HPGD (0.61) | PPARDMAOBLMNAKDM4EMAPT | |
| SCHEMBL22787196 | 0.76 | CYP4F2 (0.45) | — | |
| SCHEMBL3658180 | 0.74 | ALB (0.58) | PPARDMAOB | |
| SCHEMBL3659639 | 0.74 | ALB (0.58) | PPARDMAOB | |
| SCHEMBL5392996 | 0.72 | PPARA (0.66) | PPARDMAOBLMNAHPGDALDH1A1 | |
| SCHEMBL17676666 | 0.72 | MAOB (0.46) | PPARDMAOBLMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019109188-A1 | ACYL HYDRAZONE LINKERS, METHODS AND USES THEREOF | ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) | 2019-06-13 | — | — | WO | disclosed |