SCHEMBL21098740

SCHEMBL21098740

O=C(I)OCC(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1143909 0.77 HTT (0.59)
SCHEMBL308851 0.77 HTT (0.59)
SCHEMBL28595777 0.76 HTT (0.52)
SCHEMBL968512 0.74
SCHEMBL308852 0.74
SCHEMBL21098741 0.74 SLC13A3 (0.37)
SCHEMBL19403931 0.72
SCHEMBL15161078 0.72
SCHEMBL668270 0.72 HTT (0.54)
SCHEMBL11325639 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11583532-B2 Triazolopyrimidine derivatives for use as ghrelin o-acyl transferase (GOAT) inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2023-02-21 US disclosed
US-20210344047-A1 Silicon-Based Energy Storage Devices With Fluorinated Polymer Containing Electrolyte Additives ENEVATE CORPORATION 2021-11-04 US disclosed
US-11075408-B2 Silicon-based energy storage devices with fluorinated polymer containing electrolyte additives ENEVATE CORPORATION (US) 2021-07-27 US disclosed
US-20210038603-A1 TRIAZOLOPYRIMIDINE DERIVATIVES FOR USE AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2021-02-11 US disclosed
US-20190181500-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH FLUORINATED POLYMER CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2019-06-13 US disclosed