SCHEMBL21098741

SCHEMBL21098741

O=C(I)OCCC(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC13A3 Q8WWT9 1/20 0.37
HTT P42858 1/20 0.34
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21098770 0.86 MAOB (0.33) HTT
SCHEMBL18467706 0.83
SCHEMBL18467680 0.81
SCHEMBL608122 0.79 SLC13A3 (0.39) SLC13A3HTTRAB9A
SCHEMBL22759030 0.78
SCHEMBL21633236 0.77 SLC13A3 (0.38) SLC13A3HTTRAB9A
SCHEMBL608123 0.77 SLC13A3 (0.38) SLC13A3HTTRAB9A
SCHEMBL21357981 0.75 ADRA2A (0.44) SLC13A3HTTRAB9A
SCHEMBL2823246 0.75 SLC13A3 (0.40) SLC13A3HTTRAB9A
SCHEMBL124955 0.75 ALDH1A1 (0.46) SLC13A3HTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11591362-B2 Orthogonal protecting groups for the preparation of stereodefined phosphorothioate oligonucleotides ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) 2023-02-28 US disclosed
US-11075408-B2 Silicon-based energy storage devices with fluorinated polymer containing electrolyte additives ENEVATE CORPORATION (US) 2021-07-27 US disclosed
US-20210179658-A1 ORTHOGONAL PROTECTING GROUPS FOR THE PREPARATION OF STEREODEFINED PHOSPHOROTHIOATE OLIGONUCLEOTIDES ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) 2021-06-17 US disclosed
US-20190181500-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH FLUORINATED POLYMER CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2019-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210179658-A1 ORTHOGONAL PROTECTING GROUPS FOR THE PREPARATION OF STEREODEFINED PHOSPHOROTHIOATE OLIGONUCLEOTIDES PCNA, RNGTT, POLL SLC13A3 1861/4885HTT 1800/4885RAB9A 4560/4885
US-11591362-B2 Orthogonal protecting groups for the preparation of stereodefined phosphorothioate oligonucleotides PCNA, RNGTT, POLL SLC13A3 1861/4885HTT 1800/4885RAB9A 4560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.