SCHEMBL21099291

SCHEMBL21099291

CCCC(CC)Cc1cccs1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.46
TSHR P16473 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
HTT P42858 2/20 0.42
GLA P06280 1/20 0.42
RAB9A P51151 2/20 0.41
TAAR1 Q96RJ0 1/20 0.38
CTSC P53634 2/20 0.37
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CYP2D6 P10635 2/20 0.36
CYP3A4 P08684 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
KCNH2 Q12809 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20441722 0.92 CYP2C19 (0.48) CYP2C19TSHRL3MBTL1HTTGLA
SCHEMBL868622 0.89 TSHR (0.54) CYP2C19TSHRL3MBTL1HTTGLA
SCHEMBL19822079 0.88 CYP2C19 (0.52) CYP2C19TSHRL3MBTL1HTTGLA
SCHEMBL23688797 0.86 TSHR (0.48) CYP2C19TSHRL3MBTL1HTTGLA
SCHEMBL27986203 0.86 TSHR (0.48) CYP2C19TSHRL3MBTL1HTTGLA
SCHEMBL30532987 0.84 CYP2C19 (0.42) CYP2C19TSHRL3MBTL1HTTGLA
SCHEMBL28101182 0.84 TAAR1 (0.46) CYP2C19TSHRL3MBTL1HTTGLA
SCHEMBL18400718 0.83 L3MBTL1 (0.42) CYP2C19TSHRL3MBTL1HTTGLA
SCHEMBL31118114 0.81 TAAR1 (0.47) CYP2C19TSHRL3MBTL1HTTGLA
SCHEMBL21608630 0.81 TSHR (0.49) CYP2C19TSHRL3MBTL1HTTGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115612310-B Porphyrin photosensitive dye and application thereof 杭州中美华东制药有限公司 2023-10-27 CN disclosed
CN-115612310-A Porphyrin photosensitive dye and application thereof 杭州中美华东制药有限公司 2023-01-17 CN disclosed
WO-2019118313-A1 IMIDAZO [1,2-C] QUINAZOLIN-5-AMINE COMPOUNDS WITH A2A ANTAGONIST PROPERTIES MERCK SHARP & DOHME CORP. (US) 2019-06-20 WO disclosed