Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 9/20 | 0.60 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.57 |
| ▸ | EGFR | P00533 | 5/20 | 0.56 |
| ▸ | INSR | P06213 | 7/20 | 0.53 |
| ▸ | IGF1R | P08069 | 7/20 | 0.53 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.50 |
| ▸ | AXL | P30530 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21099421 | 0.94 | ALK (0.63) | ALKPTK2EGFRINSRIGF1R | |
| SCHEMBL21099505 | 0.92 | ALK (0.59) | ALKPTK2EGFRINSRIGF1R | |
| SCHEMBL21100267 | 0.92 | ALK (0.61) | ALKPTK2EGFRINSRIGF1R | |
| SCHEMBL21099614 | 0.91 | ALK (0.59) | ALKPTK2EGFRINSRIGF1R | |
| SCHEMBL21099507 | 0.87 | ALK (0.59) | ALKPTK2EGFRINSRIGF1R | |
| SCHEMBL21099658 | 0.86 | ALK (0.60) | ALKPTK2EGFRINSRIGF1R | |
| SCHEMBL21099509 | 0.86 | ALK (0.58) | ALKPTK2EGFRINSRIGF1R | |
| SCHEMBL21149595 | 0.86 | EGFR (0.71) | ALKPTK2EGFR | |
| SCHEMBL21099503 | 0.86 | ALK (0.60) | ALKPTK2EGFRINSRIGF1R | |
| SCHEMBL19867179 | 0.86 | ALK (0.70) | ALKPTK2EGFRINSRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3498716-A1 | THIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS | Hongyun Biotech Co., Ltd. (CN) | 2019-06-19 | — | — | EP | disclosed |