Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 4/20 | 0.52 |
| ▸ | PLK1 | P53350 | 8/20 | 0.52 |
| ▸ | IGF1R | P08069 | 12/20 | 0.49 |
| ▸ | INSR | P06213 | 3/20 | 0.49 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.44 |
| ▸ | ROS1 | P08922 | 2/20 | 0.44 |
| ▸ | FER | P16591 | 2/20 | 0.44 |
| ▸ | LTK | P29376 | 2/20 | 0.44 |
| ▸ | AXL | P30530 | 2/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.44 |
| ▸ | CLK2 | P49760 | 2/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.44 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.44 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19867232 | 0.88 | ALK (0.62) | ALKPLK1IGF1RINSRDAPK3 | |
| SCHEMBL21099560 | 0.87 | ALK (0.59) | ALKPLK1IGF1RINSRDAPK3 | |
| SCHEMBL21099491 | 0.81 | PLK1 (0.60) | ALKPLK1IGF1RINSRDAPK3 | |
| SCHEMBL21099630 | 0.81 | PLK1 (0.55) | ALKPLK1IGF1RINSRDAPK3 | |
| SCHEMBL19867327 | 0.80 | PLK1 (0.57) | ALKPLK1IGF1RINSRDAPK3 | |
| SCHEMBL21100226 | 0.78 | PTK2 (0.57) | ALKIGF1RPTK2TNK2JAK2 | |
| SCHEMBL19867350 | 0.78 | ALK (0.66) | ALKPLK1IGF1RINSRDAPK3 | |
| SCHEMBL21099448 | 0.78 | ALK (0.59) | ALKPLK1IGF1RINSRDAPK3 | |
| SCHEMBL21099676 | 0.77 | ALK (0.77) | ALKPLK1IGF1RINSRDAPK3 | |
| SCHEMBL21099569 | 0.77 | IGF1R (0.53) | ALKPLK1IGF1RINSRMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3498716-A1 | THIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS | Hongyun Biotech Co., Ltd. (CN) | 2019-06-19 | — | — | EP | disclosed |