Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 4/20 | 0.57 |
| ▸ | EGFR | P00533 | 13/20 | 0.55 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21099590 | 0.92 | ALK (0.59) | PTK2EGFRALKIGF1R | |
| SCHEMBL21099576 | 0.87 | PTK2 (0.52) | PTK2EGFRALKJAK2 | |
| SCHEMBL21150903 | 0.85 | ALK (0.62) | PTK2EGFRALKJAK2SRC | |
| SCHEMBL21150948 | 0.80 | ALK (0.66) | PTK2EGFRALKJAK2SRC | |
| SCHEMBL21099501 | 0.79 | ALK (0.52) | PTK2EGFRALKTNK2IGF1R | |
| SCHEMBL21099658 | 0.79 | ALK (0.60) | PTK2EGFRALKJAK2SRC | |
| SCHEMBL21099457 | 0.78 | ALK (0.52) | PTK2EGFRALKJAK2TNK2 | |
| SCHEMBL19867198 | 0.78 | ALK (0.75) | PTK2EGFRALKJAK2SRC | |
| SCHEMBL21099502 | 0.77 | ALK (0.59) | PTK2EGFRALKJAK2TNK2 | |
| SCHEMBL19921165 | 0.77 | ALK (0.49) | PTK2EGFRALKJAK2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3498716-A1 | THIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS | Hongyun Biotech Co., Ltd. (CN) | 2019-06-19 | — | — | EP | disclosed |