Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 4/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4402941 | 0.80 | SIGMAR1 (0.50) | SIGMAR1CHRM5CHRM1CHRM2CHRM4 | |
| SCHEMBL17722640 | 0.78 | SIGMAR1 (0.53) | SIGMAR1CHRM5CHRM1CHRM2CHRM4 | |
| SCHEMBL17722612 | 0.78 | SIGMAR1 (0.53) | SIGMAR1CHRM5CHRM1CHRM2CHRM4 | |
| SCHEMBL17722606 | 0.78 | SIGMAR1 (0.53) | SIGMAR1CHRM5CHRM1CHRM2CHRM4 | |
| SCHEMBL21910711 | 0.78 | SIGMAR1 (0.52) | SIGMAR1CHRM5CHRM1CHRM2CHRM4 | |
| SCHEMBL23023701 | 0.77 | POLB (0.51) | SIGMAR1CHRM5CHRM1CHRM2CHRM4 | |
| SCHEMBL19677041 | 0.77 | SIGMAR1 (0.50) | SIGMAR1CHRM5CHRM1CHRM2CHRM4 | |
| SCHEMBL18021940 | 0.77 | POLB (0.51) | SIGMAR1CHRM5CHRM1CHRM2CHRM4 | |
| SCHEMBL23023818 | 0.77 | SIGMAR1 (0.50) | SIGMAR1CHRM5CHRM1CHRM2CHRM4 | |
| SCHEMBL18709278 | 0.77 | SIGMAR1 (0.48) | SIGMAR1CHRM5CHRM1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019118313-A1 | IMIDAZO [1,2-C] QUINAZOLIN-5-AMINE COMPOUNDS WITH A2A ANTAGONIST PROPERTIES | MERCK SHARP & DOHME CORP. (US) | 2019-06-20 | — | — | WO | disclosed |