SCHEMBL21099772

NC(=O)[C@@H](N)CCCCNC(O)CC[C@H](NC(=O)CC[C@H](NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	8/20	0.58

▸	NOD1	Q9Y239	4/20	0.45

▸	CCKAR	P32238	8/20	0.43

▸	CCKBR	P32239	8/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21242824	0.93	GLP1R (0.60)	GLP1RNOD1CCKARCCKBR
SCHEMBL21099666	0.92	GLP1R (0.65)	GLP1RNOD1CCKARCCKBR
SCHEMBL17682360	0.91	GLP1R (0.63)	GLP1RNOD1CCKARCCKBR
SCHEMBL20653031	0.91	GLP1R (0.66)	GLP1RNOD1CCKARCCKBR
SCHEMBL20900411	0.89	GLP1R (0.58)	GLP1RNOD1
SCHEMBL21099901	0.89	GLP1R (0.62)	GLP1RNOD1CCKARCCKBR
SCHEMBL19034932	0.87	GLP1R (0.67)	GLP1RNOD1CCKARCCKBR
SCHEMBL19034971	0.87	GLP1R (0.67)	GLP1RNOD1CCKARCCKBR
SCHEMBL19034982	0.86	GLP1R (0.65)	GLP1RNOD1
SCHEMBL19034800	0.86	GLP1R (0.65)	GLP1RNOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2986313-B1	STABLE, PROTRACTED GLP-1/GLUCAGON RECEPTOR CO-AGONISTS FOR MEDICAL USE	NOVO NORDISK AS (DK)	2019-06-12	—	—	EP	disclosed