SCHEMBL21099786

C[C@@H](OC(=O)c1ccccc1)[C@H]1O[C@@](C)(n2ccc(=O)[nH]c2=O)[C@H](OC(=O)c2ccccc2)[C@@H]1OC(=O)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	POLB	P06746	2/20	0.35

▸	MEN1	O00255	1/20	0.35

▸	USP2	O75604	1/20	0.35

▸	KMT2A	Q03164	1/20	0.35

▸	ABCB1	P08183	8/20	0.35

▸	HSD17B10	Q99714	1/20	0.34

▸	SLC43A1	O75387	1/20	0.33

▸	GAA	P10253	1/20	0.33

▸	CHRM2	P08172	1/20	0.32

▸	CHRM4	P08173	1/20	0.32

▸	CHRM1	P11229	1/20	0.32

▸	CHRM3	P20309	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21100413	0.91	POLB (0.33)	POLBMEN1USP2KMT2AABCB1
SCHEMBL13470609	0.86	POLB (0.34)	POLBMEN1USP2KMT2AABCB1
SCHEMBL13470531	0.84	ABCB1 (0.34)	POLBMEN1USP2KMT2AABCB1
SCHEMBL21099784	0.82	POLB (0.33)	POLBMEN1USP2KMT2AABCB1
SCHEMBL13470537	0.81	POLB (0.34)	POLBMEN1USP2KMT2AHSD17B10
SCHEMBL13470535	0.81	POLB (0.34)	POLBMEN1USP2KMT2AHSD17B10
SCHEMBL16214806	0.80	MEN1 (0.31)	POLBMEN1USP2KMT2A
SCHEMBL21099791	0.79	POLB (0.35)	POLBMEN1USP2KMT2AHSD17B10
SCHEMBL21100115	0.77	TLR7 (0.36)	POLBKMT2AHSD17B10GAA
SCHEMBL23710652	0.75	POLB (0.46)	POLBMEN1USP2KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2697241-B1	1'-SUBSTITUTED PYRIMIDINE N-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT	GILEAD SCIENCES INC (US)	2019-06-12	—	—	EP	disclosed