Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | DUT | P33316 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21099790 | 0.80 | CRBN (0.33) | DUT | |
| SCHEMBL21099786 | 0.77 | POLB (0.35) | POLBHSD17B10GAAKMT2A | |
| SCHEMBL21100413 | 0.73 | POLB (0.33) | POLBHSD17B10GAAKMT2A | |
| SCHEMBL13470537 | 0.72 | POLB (0.34) | POLBHSD17B10NPC1CYP3A4CYP2C9 | |
| SCHEMBL13470535 | 0.72 | POLB (0.34) | POLBHSD17B10NPC1CYP3A4CYP2C9 | |
| SCHEMBL21099791 | 0.70 | POLB (0.35) | POLBHSD17B10CYP3A4CYP2C9DUT | |
| SCHEMBL13470531 | 0.69 | ABCB1 (0.34) | POLBHSD17B10KMT2A | |
| SCHEMBL13470609 | 0.69 | POLB (0.34) | TLR7POLBHSD17B10NPC1KMT2A | |
| SCHEMBL805145 | 0.68 | CYP3A4 (0.45) | POLBHSD17B10CYP3A4CYP2C9DUT | |
| SCHEMBL21099784 | 0.68 | POLB (0.33) | POLBHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697241-B1 | 1'-SUBSTITUTED PYRIMIDINE N-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES INC (US) | 2019-06-12 | — | — | EP | disclosed |