Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 8/20 | 0.32 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.31 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.31 |
| ▸ | DUT | P33316 | 2/20 | 0.31 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.30 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21100115 | 0.80 | TLR7 (0.36) | DUT | |
| SCHEMBL21099905 | 0.79 | SLC28A1 (0.35) | CRBNP2RY6SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL21100387 | 0.79 | SLC28A1 (0.35) | CRBNP2RY6SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL30676683 | 0.74 | SLC28A1 (0.36) | CRBNP2RY6SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL13470539 | 0.71 | CRBN (0.31) | CRBNDUT | |
| SCHEMBL17770830 | 0.70 | CRBN (0.39) | CRBNP2RY6SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL6002015 | 0.69 | SLC28A1 (0.50) | CRBNP2RY6SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL42133 | 0.69 | SLC28A1 (0.50) | CRBNP2RY6SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL12658269 | 0.69 | SLC28A1 (0.50) | CRBNP2RY6SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL784550 | 0.69 | SLC28A1 (0.41) | CRBNP2RY6SLC28A1SLC28A2SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697241-B1 | 1'-SUBSTITUTED PYRIMIDINE N-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES INC (US) | 2019-06-12 | — | — | EP | disclosed |