Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ADH1B | P00325 | 2/20 | 0.41 |
| ▸ | ADH1C | P00326 | 2/20 | 0.41 |
| ▸ | ADH1A | P07327 | 2/20 | 0.41 |
| ▸ | ADH7 | P40394 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ADH4 | P08319 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28756013 | 0.82 | TSHR (0.46) | TSHRADH1BADH1CADH1AADH7 | |
| SCHEMBL25750315 | 0.82 | TSHR (0.46) | TSHRADH1BADH1CADH1AADH7 | |
| SCHEMBL14049815 | 0.81 | ADH1B (0.59) | TSHRHIF1AADH1BADH1CADH1A | |
| SCHEMBL17128629 | 0.81 | ADH1B (0.59) | TSHRHIF1AADH1BADH1CADH1A | |
| SCHEMBL5967504 | 0.81 | ADH1B (0.59) | TSHRHIF1AADH1BADH1CADH1A | |
| SCHEMBL20969492 | 0.81 | ADH1B (0.36) | ADH1BADH1CADH1AADH7EPHX1 | |
| SCHEMBL13692972 | 0.78 | — | — | |
| SCHEMBL24447300 | 0.78 | TSHR (0.34) | TSHRHIF1AFAAHTRPV1 | |
| SCHEMBL2285298 | 0.75 | ADH1B (0.52) | TSHRADH1BADH1CADH1AADH7 | |
| SCHEMBL2282753 | 0.75 | ADH1B (0.52) | TSHRADH1BADH1CADH1AADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2986313-B1 | STABLE, PROTRACTED GLP-1/GLUCAGON RECEPTOR CO-AGONISTS FOR MEDICAL USE | NOVO NORDISK AS (DK) | 2019-06-12 | — | — | EP | disclosed |