Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29411509 | 0.83 | ALDH1A1 (0.69) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL21045420 | 0.83 | ALDH1A1 (0.69) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29411464 | 0.81 | KMT2A (0.66) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL21045258 | 0.81 | KMT2A (0.66) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL24968055 | 0.78 | MAPT (0.72) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL21045079 | 0.77 | MAPT (0.74) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29411505 | 0.77 | MAPT (0.74) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL21045207 | 0.76 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29411541 | 0.76 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL24967599 | 0.75 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113242-A1 | TUBULIN INHIBITORS | Lin BioScience, LLC (US) | 2019-06-13 | — | — | WO | disclosed |