Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29411568 | 0.86 | L3MBTL1 (0.56) | L3MBTL1LMNAMAPK1ATMTDP1 | |
| SCHEMBL21045342 | 0.86 | L3MBTL1 (0.56) | L3MBTL1LMNAMAPK1ATMTDP1 | |
| SCHEMBL21045171 | 0.71 | NPC1 (0.57) | L3MBTL1LMNAMAPK1ATMTDP1 | |
| SCHEMBL29411389 | 0.71 | NPC1 (0.57) | L3MBTL1LMNAMAPK1ATMTDP1 | |
| SCHEMBL21045552 | 0.71 | CYP3A4 (0.40) | L3MBTL1LMNAMAPK1ATMTDP1 | |
| SCHEMBL29411460 | 0.71 | CYP3A4 (0.40) | L3MBTL1LMNAMAPK1ATMTDP1 | |
| SCHEMBL29411507 | 0.68 | NPC1 (0.70) | L3MBTL1LMNAMAPK1ATMTDP1 | |
| SCHEMBL21045514 | 0.68 | NPC1 (0.70) | L3MBTL1LMNAMAPK1ATMTDP1 | |
| SCHEMBL21045259 | 0.67 | NPC1 (0.62) | L3MBTL1LMNAMAPK1ATMTDP1 | |
| SCHEMBL29411556 | 0.67 | NPC1 (0.62) | L3MBTL1LMNAMAPK1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113242-A1 | TUBULIN INHIBITORS | Lin BioScience, LLC (US) | 2019-06-13 | — | — | WO | disclosed |