Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.31 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29411438 | 0.89 | ALOX5AP (0.41) | ALOX5APFEN1ALDH1A1L3MBTL1CNR2 | |
| SCHEMBL21045107 | 0.89 | ALOX5AP (0.41) | ALOX5APFEN1ALDH1A1L3MBTL1CNR2 | |
| SCHEMBL29411638 | 0.83 | L3MBTL1 (0.46) | ALOX5APFEN1ALDH1A1L3MBTL1ATM | |
| SCHEMBL21045508 | 0.83 | L3MBTL1 (0.46) | ALOX5APFEN1ALDH1A1L3MBTL1ATM | |
| SCHEMBL21045338 | 0.69 | MAPK1 (0.44) | ALDH1A1L3MBTL1ATMTDP1MAPK1 | |
| SCHEMBL29411392 | 0.69 | MAPK1 (0.44) | ALDH1A1L3MBTL1ATMTDP1MAPK1 | |
| SCHEMBL29411389 | 0.66 | NPC1 (0.57) | ALDH1A1L3MBTL1ATMTDP1LMNA | |
| SCHEMBL21045171 | 0.66 | NPC1 (0.57) | ALDH1A1L3MBTL1ATMTDP1LMNA | |
| SCHEMBL21045507 | 0.64 | L3MBTL1 (0.47) | ALDH1A1L3MBTL1CNR2ATMTDP1 | |
| SCHEMBL29411661 | 0.64 | L3MBTL1 (0.47) | ALDH1A1L3MBTL1CNR2ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113242-A1 | TUBULIN INHIBITORS | Lin BioScience, LLC (US) | 2019-06-13 | — | — | WO | disclosed |