⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21136843 | 0.83 | — | — | |
| SCHEMBL21101216 | 0.69 | — | — | |
| SCHEMBL21498170 | 0.69 | — | — | |
| SCHEMBL9910016 | 0.65 | — | — | |
| SCHEMBL16213785 | 0.63 | — | — | |
| SCHEMBL13054913 | 0.63 | — | — | |
| SCHEMBL22739144 | 0.63 | — | — | |
| SCHEMBL14030432 | 0.62 | — | — | |
| SCHEMBL9910021 | 0.62 | HSD11B1 (0.31) | — | |
| SCHEMBL18085982 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10428070-B2 | Hepatitis B antiviral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2019-10-01 | — | — | US | disclosed |
| US-20190177320-A1 | HEPATITIS B ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2019-06-13 | — | — | US | disclosed |