Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 14/20 | 0.54 |
| ▸ | MAOB | P27338 | 9/20 | 0.54 |
| ▸ | MAOA | P21397 | 6/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14885503 | 1.00 | KDM1A (0.54) | KDM1AMAOBMAOAESR2SMN1; SMN2 | |
| SCHEMBL7004176 | 0.79 | KDM1A (0.49) | KDM1AMAOBMAOA | |
| SCHEMBL19466144 | 0.79 | KDM1A (0.52) | KDM1AMAOBMAOA | |
| SCHEMBL27965824 | 0.79 | KDM1A (0.52) | KDM1AMAOBMAOA | |
| SCHEMBL7004171 | 0.79 | KDM1A (0.49) | KDM1AMAOBMAOA | |
| SCHEMBL12308294 | 0.78 | KDM1A (0.65) | KDM1AMAOBMAOASMN1; SMN2NPSR1 | |
| SCHEMBL12015667 | 0.78 | KDM1A (0.65) | KDM1AMAOBMAOASMN1; SMN2NPSR1 | |
| SCHEMBL11955769 | 0.78 | KDM1A (0.65) | KDM1AMAOBMAOASMN1; SMN2NPSR1 | |
| SCHEMBL12878038 | 0.78 | KDM1A (0.65) | KDM1AMAOBMAOASMN1; SMN2NPSR1 | |
| SCHEMBL12797016 | 0.78 | KDM1A (0.65) | KDM1AMAOBMAOASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2688568-B1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2019-06-19 | — | — | EP | disclosed |