Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.49 |
| ▸ | MAOB | P27338 | 5/20 | 0.49 |
| ▸ | MAOA | P21397 | 4/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7004171 | 1.00 | KDM1A (0.49) | KDM1AMAOBMAOAMDM2HTR2A | |
| Hydrochloric Acid SCHEMBL4138450 | 0.93 | KDM1A (0.51) | KDM1AMAOBMAOAMDM2HTR2A | |
| SCHEMBL18416962 | 0.80 | KDM1A (0.42) | KDM1AMAOBMAOASLC6A3 | |
| SCHEMBL18416963 | 0.80 | KDM1A (0.42) | KDM1AMAOBMAOASLC6A3 | |
| SCHEMBL27965824 | 0.79 | KDM1A (0.52) | KDM1AMAOBMAOAHTR2AHTR2C | |
| SCHEMBL21101247 | 0.79 | KDM1A (0.54) | KDM1AMAOBMAOA | |
| SCHEMBL19466144 | 0.79 | KDM1A (0.52) | KDM1AMAOBMAOAHTR2AHTR2C | |
| SCHEMBL14885503 | 0.79 | KDM1A (0.54) | KDM1AMAOBMAOA | |
| SCHEMBL15778201 | 0.79 | KDM1A (0.57) | KDM1AMAOBMAOAHTR2AHTR2C | |
| SCHEMBL12015667 | 0.78 | KDM1A (0.65) | KDM1AMAOBMAOAHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097153-B1 | NOVEL TRIAZOLO[4,5-D]PYRIMIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2003-10-01 | — | — | EP | disclosed |