Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3702216 | 0.81 | TRPV1 (0.46) | AAK1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL5236189 | 0.81 | SMN1; SMN2 (0.55) | AAK1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL4271192 | 0.81 | NR4A2 (0.51) | AAK1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL16289934 | 0.81 | NPC1 (0.41) | AAK1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL2209996 | 0.81 | TRPV1 (0.43) | AAK1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL30880730 | 0.81 | TRPV1 (0.43) | AAK1NPC1RAB9ASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL30880572 | 0.79 | NPC1 (0.42) | AAK1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL20460397 | 0.79 | RUNX1 (0.54) | AAK1LMNARUNX1MAPK1KDM4E | |
| SCHEMBL18544268 | 0.78 | KDM4E (0.60) | LMNACYP1A2MAPK1KDM4E | |
| SCHEMBL15129852 | 0.76 | LMNA (0.68) | SMN1; SMN2LMNATP53CYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2804859-B1 | NOVEL FAP INHIBITORS | UNIV ANTWERPEN (BE) | 2019-06-12 | — | — | EP | disclosed |