Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | PDE2A | O00408 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17570863 | 0.88 | ATM (0.41) | KDM4EALDH1A1HPGDSMN1; SMN2PDE10A | |
| SCHEMBL17570856 | 0.88 | KDM4E (0.46) | KDM4EALDH1A1HPGDSMN1; SMN2PDE2A | |
| SCHEMBL17570857 | 0.84 | KDM4E (0.46) | KDM4EALDH1A1HPGDSMN1; SMN2PDE2A | |
| SCHEMBL1698065 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1HPGDSMN1; SMN2AURKA | |
| Carbazole SCHEMBL16433320 | 0.76 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDSMN1; SMN2AURKA | |
| SCHEMBL21346496 | 0.76 | CDC25B (0.43) | KDM4EALDH1A1HPGDSMN1; SMN2PDE2A | |
| SCHEMBL21415948 | 0.75 | KDM4E (0.42) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL23504054 | 0.74 | KDM4E (0.42) | KDM4EALDH1A1HPGDPDE2APDE10A | |
| SCHEMBL18463241 | 0.74 | AURKA (0.48) | KDM4EALDH1A1HPGDSMN1; SMN2PDE2A | |
| SCHEMBL15631599 | 0.72 | KDM4E (0.46) | KDM4EALDH1A1HPGDSMN1; SMN2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2993215-B1 | Azabenzimidazo[2,1-a]benzimidazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2019-06-19 | — | — | EP | disclosed |