Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | C1R | P00736 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29404834 | 0.83 | PARP1 (0.50) | PARP1ALDH1A1CYP1A2HPGDALOX15 | |
| SCHEMBL6465602 | 0.83 | PARP1 (0.50) | PARP1ALDH1A1CYP1A2HPGDALOX15 | |
| SCHEMBL18848334 | 0.83 | ALDH1A1 (0.36) | PARP1ALDH1A1HPGDALOX15KDM4E | |
| SCHEMBL15139040 | 0.76 | NR4A2 (0.52) | PARP1ALDH1A1CYP1A2HPGDALOX15 | |
| SCHEMBL4620129 | 0.76 | PARP1 (0.44) | PARP1ALDH1A1CYP1A2HPGDALOX15 | |
| SCHEMBL20444679 | 0.76 | PDPK1 (0.47) | PARP1ALDH1A1CYP1A2HPGDALOX15 | |
| SCHEMBL7461243 | 0.76 | PARP1 (0.44) | PARP1ALDH1A1CYP1A2HPGDALOX15 | |
| SCHEMBL8603889 | 0.72 | PARP1 (0.44) | PARP1ALDH1A1CYP1A2HPGDALOX15 | |
| SCHEMBL9984695 | 0.72 | PARP1 (0.44) | PARP1ALDH1A1CYP1A2HPGDALOX15 | |
| SCHEMBL2221871 | 0.72 | PDPK1 (0.52) | PARP1ALDH1A1CYP1A2HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2804859-B1 | NOVEL FAP INHIBITORS | UNIV ANTWERPEN (BE) | 2019-06-12 | — | — | EP | disclosed |