Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 13/20 | 0.75 |
| ▸ | FAP | Q12884 | 8/20 | 0.55 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.55 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26763770 | 0.87 | PREP (0.61) | PREPFAPDPP7DPP9 | |
| SCHEMBL26223829 | 0.86 | PREP (0.74) | PREPFAPDPP7 | |
| SCHEMBL21101376 | 0.86 | PREP (0.74) | PREPFAPDPP7 | |
| SCHEMBL15129856 | 0.86 | PREP (1.00) | PREPFAPDPP7DPP9 | |
| SCHEMBL15129855 | 0.86 | PREP (1.00) | PREPFAPDPP7DPP9 | |
| SCHEMBL21101556 | 0.82 | PREP (0.66) | PREPFAPDPP9 | |
| SCHEMBL26763766 | 0.81 | PREP (0.58) | PREPFAPDPP7 | |
| SCHEMBL26231103 | 0.81 | PREP (0.77) | PREPFAPDPP7DPP9 | |
| SCHEMBL24928039 | 0.79 | PREP (0.57) | PREPFAPDPP7DPP9 | |
| SCHEMBL25474208 | 0.79 | PREP (0.64) | PREPFAPDPP7DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2804859-B1 | NOVEL FAP INHIBITORS | UNIV ANTWERPEN (BE) | 2019-06-12 | — | — | EP | disclosed |