Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.74 |
| ▸ | FAP | Q12884 | 17/20 | 0.73 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26223829 | 1.00 | PREP (0.74) | PREPFAPDPP7 | |
| SCHEMBL21101555 | 0.86 | PREP (0.75) | PREPFAPDPP7 | |
| SCHEMBL22811116 | 0.86 | FAP (0.77) | PREPFAP | |
| SCHEMBL15129801 | 0.85 | PREP (1.00) | PREPFAPDPP7 | |
| SCHEMBL15129800 | 0.85 | PREP (1.00) | PREPFAPDPP7 | |
| SCHEMBL26763770 | 0.85 | PREP (0.61) | PREPFAPDPP7 | |
| SCHEMBL24927935 | 0.85 | FAP (0.73) | PREPFAPDPP7 | |
| SCHEMBL16267187 | 0.85 | PREP (1.00) | PREPFAPDPP7 | |
| SCHEMBL15138980 | 0.85 | PREP (1.00) | PREPFAPDPP7 | |
| SCHEMBL29181978 | 0.85 | FAP (0.73) | PREPFAPDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2804859-B1 | NOVEL FAP INHIBITORS | UNIV ANTWERPEN (BE) | 2019-06-12 | — | — | EP | disclosed |