Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.44 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.33 |
| ▸ | WHR1 | P49842 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8258122 | 0.92 | HRH3 (0.41) | HRH3HTR4KDM1AALDH1A1WHR1 | |
| SCHEMBL14453901 | 0.87 | HRH3 (0.38) | HRH3HTR4KDM1AALDH1A1WHR1 | |
| SCHEMBL19083162 | 0.83 | HRH3 (0.36) | HRH3 | |
| SCHEMBL19779743 | 0.82 | HRH3 (0.36) | HRH3 | |
| SCHEMBL21725268 | 0.81 | HRH3 (0.35) | HRH3ALDH1A1FLT3TYRO3MERTK | |
| SCHEMBL3816722 | 0.79 | HRH3 (0.40) | HRH3HTR4KDM1AALDH1A1ADRB3 | |
| SCHEMBL14472413 | 0.79 | MEN1 (0.41) | HRH3KDM1AADRB3MAOB | |
| SCHEMBL2617741 | 0.78 | HRH3 (0.39) | HRH3HTR4KDM1AALDH1A1ADRB3 | |
| SCHEMBL2616311 | 0.77 | NCF1 (0.48) | HRH3KDM1AMAOB | |
| SCHEMBL16015325 | 0.75 | HRH3 (0.43) | HRH3KDM1AALDH1A1WHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2688568-B1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2019-06-19 | — | — | EP | disclosed |