Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3157826 | 0.86 | FFAR4 (0.53) | FFAR4GRIN2BDDR1TRPV1HDAC3 | |
| SCHEMBL3153601 | 0.82 | POLB (0.46) | FFAR4GRIN2BDDR1TRPV1HDAC3 | |
| SCHEMBL4660711 | 0.82 | FFAR4 (0.40) | FFAR4GRIN2BDDR1TRPV1HDAC3 | |
| SCHEMBL21102126 | 0.80 | MARS1 (0.43) | FFAR4GRIN2BCNR1POLB | |
| SCHEMBL8198914 | 0.80 | GRIN2B (0.44) | FFAR4GRIN2BDDR1TRPV1HDAC3 | |
| SCHEMBL3161791 | 0.78 | GRIN2B (0.47) | FFAR4GRIN2BDDR1TRPV1HDAC3 | |
| SCHEMBL28195942 | 0.78 | GRIN2B (0.43) | FFAR4GRIN2BDDR1TRPV1HDAC3 | |
| SCHEMBL48901 | 0.77 | IDO1 (0.43) | CNR1POLB | |
| SCHEMBL13749634 | 0.77 | GRIN2B (0.41) | FFAR4GRIN2BDDR1TRPV1HDAC3 | |
| SCHEMBL11546048 | 0.76 | CHRM2 (0.51) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019111225-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF NON‑ALCOHOLIC STEATOHEPATITIS | AVALIV THERAPEUTICS (US) | 2019-06-13 | — | — | WO | disclosed |