Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | PDE6D | O43924 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21101678 | 0.98 | THRB (0.44) | THRBBACE1PDE6DTYMSTHRA | |
| SCHEMBL15338966 | 0.98 | THRB (0.42) | THRBBACE1PDE6DTYMSTHRA | |
| SCHEMBL17625741 | 0.92 | THRB (0.44) | THRBBACE1PDE6DTYMSTHRA | |
| SCHEMBL15339212 | 0.91 | THRB (0.38) | THRBBACE1PDE6DTYMSTHRA | |
| SCHEMBL17625776 | 0.90 | BACE1 (0.51) | THRBBACE1PDE6DTYMSTHRA | |
| SCHEMBL15338917 | 0.90 | THRB (0.46) | THRBBACE1PDE6DTYMSTHRA | |
| SCHEMBL15339166 | 0.90 | THRB (0.37) | THRBBACE1PDE6DTYMSTHRA | |
| SCHEMBL15339124 | 0.89 | THRB (0.39) | THRBBACE1PDE6DTYMSTHRA | |
| SCHEMBL18806057 | 0.89 | THRB (0.45) | THRBBACE1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL15339169 | 0.89 | THRB (0.41) | THRBBACE1PDE6DTYMSTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11015122-B2 | Liquid crystal composition and liquid crystal display element | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) | 2021-05-25 | — | — | US | disclosed |
| US-20190185752-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | Shijiazhuang Chengzhi Yonghua Display Material Co., Ltd (CN) | 2019-06-20 | — | — | US | disclosed |