Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 10/20 | 0.75 |
| ▸ | DPP4 | P27487 | 2/20 | 0.60 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.60 |
| ▸ | FAP | Q12884 | 10/20 | 0.58 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26231103 | 0.89 | PREP (0.77) | PREPDPP4DPP9FAPDPP7 | |
| SCHEMBL15129913 | 0.86 | PREP (1.00) | PREPDPP4DPP9FAPDPP7 | |
| SCHEMBL29936567 | 0.86 | PREP (1.00) | PREPDPP4DPP9FAPDPP7 | |
| SCHEMBL15129912 | 0.86 | PREP (1.00) | PREPDPP4DPP9FAPDPP7 | |
| SCHEMBL21101295 | 0.83 | PREP (0.68) | PREPDPP4DPP9FAP | |
| SCHEMBL25474208 | 0.79 | PREP (0.64) | PREPDPP4DPP9FAPDPP7 | |
| SCHEMBL30783512 | 0.79 | PREP (0.87) | PREPDPP4DPP9FAPDPP7 | |
| SCHEMBL27260380 | 0.79 | PREP (0.87) | PREPDPP4DPP9FAPDPP7 | |
| SCHEMBL27260394 | 0.79 | PREP (0.87) | PREPDPP4DPP9FAPDPP7 | |
| SCHEMBL26766414 | 0.78 | PREP (0.62) | PREPDPP4DPP9FAPDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2804859-B1 | NOVEL FAP INHIBITORS | UNIV ANTWERPEN (BE) | 2019-06-12 | — | — | EP | disclosed |