Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 5/20 | 0.68 |
| ▸ | DPP4 | P27487 | 2/20 | 0.60 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | FAP | Q12884 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MET | P08581 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21101294 | 0.87 | PREP (0.69) | PREPDPP4DPP9FAP | |
| SCHEMBL26231103 | 0.84 | PREP (0.77) | PREPDPP4DPP9FAP | |
| SCHEMBL21101486 | 0.84 | PREP (0.67) | PREPFAP | |
| SCHEMBL23760562 | 0.83 | LMNA (0.64) | PREPDPP4DPP9LMNAKDM4E | |
| SCHEMBL23760563 | 0.83 | LMNA (0.67) | PREPDPP4DPP9LMNAKDM4E | |
| SCHEMBL21101960 | 0.83 | PREP (0.75) | PREPDPP4DPP9FAP | |
| SCHEMBL15129913 | 0.81 | PREP (1.00) | PREPDPP4DPP9FAP | |
| SCHEMBL29936567 | 0.81 | PREP (1.00) | PREPDPP4DPP9FAP | |
| SCHEMBL15129912 | 0.81 | PREP (1.00) | PREPDPP4DPP9FAP | |
| SCHEMBL26225738 | 0.81 | FAP (0.58) | PREPDPP4DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4227300-A1 | TRUNCATED EVANS BLUE MODIFIED FIBROBLAST ACTIVATION PROTEIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Yantai Lannacheng Biotechnology Co., Ltd. (CN) | 2023-08-16 | — | — | EP | disclosed |
| EP-2804859-B1 | NOVEL FAP INHIBITORS | UNIV ANTWERPEN (BE) | 2019-06-12 | — | — | EP | disclosed |