Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.39 |
| ▸ | ACE | P12821 | 3/20 | 0.39 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.37 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.37 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL642427 | 0.84 | F2 (0.44) | DPP4F2 | |
| SCHEMBL606217 | 0.84 | F2 (0.44) | DPP4F2 | |
| SCHEMBL28128812 | 0.84 | DPP4 (0.40) | DPP4ACESPHK1SPHK2CA12 | |
| SCHEMBL608859 | 0.84 | F2 (0.44) | DPP4F2 | |
| SCHEMBL14621778 | 0.84 | ACE (0.41) | ACERENF2CA12CA1 | |
| SCHEMBL8297626 | 0.82 | ACE (0.56) | ACERENF2 | |
| Hydrochloric Acid SCHEMBL28488246 | 0.82 | SPHK1 (0.39) | DPP4SPHK1SPHK2CA12CA1 | |
| SCHEMBL13435754 | 0.81 | DPP4 (0.39) | DPP4ACERENCA12CA1 | |
| SCHEMBL8591233 | 0.79 | HTT (0.45) | DPP4ACESPHK1SPHK2CA12 | |
| SCHEMBL3817074 | 0.79 | HTT (0.45) | DPP4ACESPHK1SPHK2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019111225-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF NON‑ALCOHOLIC STEATOHEPATITIS | AVALIV THERAPEUTICS (US) | 2019-06-13 | — | — | WO | disclosed |